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Failed Back Syndrome

Failed Back and Failed Fusion Syndrome

After any spine surgery, a percentage of patients may still experience pain. This is called failed back or failed fusion syndrome, which is characterized by intractable pain and an inability to return to normal activities. Surgery may be able to fix the condition but not eliminate the pain.
Symptoms
The main symptom is pain following back surgery. Additionally, the patient’s ability to complete activities of daily living may be altered.

Causes and Risk Factors
Smoking
Formation of scar tissue
Recurring or persistent disc disease at adjacent levels
Continued pressure from spinal stenosis
Instability or abnormal movement
Pseudoarthrosis or failure of the fusion
Nerve damage within the nerve, arachnoiditis
Diagnosis
A diagnosis will be based on the patient’s symptoms and medical history.
Additional tests that may be useful include:
Magnetic resonance imaging (MRI)
Computed tomography (CT scans)
Treatment
Treatment of these conditions, once they have occurred, will vary depending on the nature of the condition and what caused prior surgery to fail.
Some patients fail to improve even after the best surgical intervention. In spite of careful diagnosis and a successful operation, patients may continue to experience pain or limitations in performing daily activities. This continuation of symptoms is known as “failed back syndrome.” A spinal fusion occurs after the surgeon creates the conditions for the bones of the spine to unite into an immobile block. The union of the fusion mass occurs over time. When the time for healing is extended or the fusion fails to unite, this is a called a “failed fusion” or pseudoarthrosis.

Article Provided By: cedars-sinai.org

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Postherpetic Neuralgia

Postherpetic Neuralgia

What Is Postherpetic Neuralgia?
Postherpetic neuralgia is a painful condition that affects your nerves and skin. It is a complication of herpes zoster, commonly called shingles.
Shingles is a painful, blistering skin rash caused by a reactivation of a virus called varicella-zoster, which people usually get in childhood or adolescence as chicken pox. The virus can remain dormant in your body’s nerve cells after childhood and can reactivate years later.
When the pain caused by shingles doesn’t go away after the rash and blisters clear up, the condition is called postherpetic neuralgia. Postherpetic neuralgia is the most common complication of shingles, and it occurs when a person’s nerves are damaged during a shingles outbreak. The damaged nerves can’t send messages from the skin to the brain and the messages become confused, resulting in chronic, severe pain that can last for months or years.
According to a study by the American Academy of Family Physicians, about 20 percent of people who get shingles also develop postherpetic neuralgia. Additionally, this condition is more likely to occur in people over the age of 60.
What Are the Symptoms of Postherpetic Neuralgia?
Shingles typically causes a painful, blistering rash. Postherpetic neuralgia is a complication that only occurs in people who already have had shingles. Common signs and symptoms of postherpetic neuralgia include:
severe pain that continues for more than one to three months in the same place that the shingles occurred, even after the rash goes away
burning sensation on the skin, even from the slightest pressure
sensitivity to touch or temperature changes

What Are the Risk Factors for Postherpetic Neuralgia?
Age is a high risk factor for getting both shingles and postherpetic neuralgia. People over 60 have an increased risk, and people over 70 have an even higher risk.
Those who have acute pain and severe rash during shingles are also at a higher risk of developing postherpetic neuralgia.
People with lowered immunity due to disorders like HIV infection and Hodgkin’s lymphoma, a type of cancer, have an increased risk of developing shingles. A study by the American Academy of Family Physicians shows that the incidence of shingles is up to 15 times greater in patients with HIV than in those who don’t have the virus.

 

How Is Postherpetic Neuralgia Diagnosed and Treated?
Tests are unnecessary. Most of the time, your doctor will diagnose postherpetic neuralgia based on the duration of pain symptoms following shingles.
Treatment for postherpetic neuralgia aims to control and reduce pain until the condition goes away. Pain therapy may include the following treatments.
Analgesics
Painkillers are also known as analgesics. Common analgesics used for postherpetic neuralgia include:
capsaicin cream: an analgesic extracted from hot chili peppers
lidocaine patches, a numbing medicine
over-the-counter medications such as acetaminophen (Tylenol), or ibuprofen (Advil)
stronger prescription drugs, such as codeine, hydrocodone, or oxycodone
Tricyclic Antidepressants
Tricyclic antidepressants are normally prescribed to treat depression, but they are also effective in treating pain caused by postherpetic neuralgia. They often have side effects, like dry mouth and blurred vision. They do not act as quickly as other types of painkillers. Commonly used tricyclic antidepressants to treat postherpetic neuralgia include:
amitriptyline (Elavil)
desipramine (Norpramin)
imipramine (Tofranil)
nortriptyline (Pamelor)
Anticonvulsants
Anticonvulsants are normally used for seizures, however clinical studies have shown that lower doses can be effective in treating pain for postherpetic neuralgia as well. Commonly used anticonvulsants include
carbamazepine (Tegretol)
pregabalin (Lyrica)
gabapentin (Neurontin)
phenytoin (Dilantin)

How Can Postherpetic Neuralgia Be Prevented?
A herpes zoster vaccine called Zostavax reduces the risk of shingles by 50 percent, and also protects against postherpetic neuralgia. The Centers for Disease Control and Prevention (CDC)
Trusted Source
recommends that the vaccine be given to all adults over the age of 60, except for people with a weakened immune system. These people may be advised not to receive the vaccine because it contains a live virus.
The herpes zoster vaccine, Zostavax, is different from the chicken pox vaccine, Varivax, that is usually given to children. Zostavax has at least 14 times more live varicella viruses than Varivax. Zostavax can’t be used in children, and Varivax can’t be used to prevent herpes zoster.

Outlook
Painful, postherpetic neuralgia is treatable and preventable. Most cases disappear in one to two months, and rare cases last longer than a year.
If you’re over the age of 60, it’s wise to get vaccinated against it. If you do develop it, there are many analgesics and even antidepressants you can take to manage the pain. It may just take some time and patience.

Article Provided By: healthline

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Diabetic Neuropathy, Pain Relief, Peripheral Neuropathy, Pain Management, Nerve Pain Treatment, Carolina Pain Scrambler, Greenville South Carolina

Idiopathic Neuropathy

Idiopathic Neuropathy

What is idiopathic neuropathy?
Neuropathy is when nerve damage interferes with the functioning of the peripheral nervous system (PNS). When the cause can’t be determined, it’s called idiopathic neuropathy.
The PNS carries information from the central nervous system (CNS), or brain and spinal cord, to the rest of the body.
There are three kinds of nerves within the PNS. Sensory nerves relay messages from the senses to the brain. This allows sensations of temperature and touch. Motor nerves transmit signals from the brain to the muscles. This helps the brain control the muscles. Autonomic nerves control body functions like heart rate, breathing, and digestion.
Damage to nerve cells can affect how the PNS communicates with the rest of the body. Symptoms can include numbness, pain, and balance issues.
It’s called acute neuropathy when symptoms develop suddenly. Alternately, it’s called chronic neuropathy when symptoms start slowly and increase over time.
Diagnosis involves physical examination and review of medical history. Diagnostic testing may include blood tests, nerve testing, and imaging tests.
There is no cure for idiopathic neuropathy. Treatments including medication, physical therapy, and lifestyle modifications can help you function and feel better.
What are the symptoms of neuropathy?
Symptoms can be vague at onset and are similar to those of other conditions. Symptoms vary depending on which nerves are damaged.
Symptoms of sensory neuropathy may include:
numbness, tingling, and burning sensation, particularly in hands and feet
vague or strange sensations (paresthesias)
pain, or inability to feel pain, touch, or temperature
lack of coordination or loss of reflexes
Symptoms of motor neuropathy may include:
muscle weakness or loss of muscle control
trouble with balance and coordination
muscle twitching, cramping, or spasms
difficulty walking or moving limbs
Symptoms of autonomic neuropathy may include:
dizziness, or fainting
sweating abnormalities
nausea, vomiting, or diarrhea
abnormal heart rate or blood pressure
sexual dysfunction
Symptoms may progress quickly and then slowly get better over time in some forms of acute neuropathy. Some chronic neuropathies cause periods of relapse followed by periods of remission.
What are the causes of neuropathy?
Some conditions that cause neuropathy are hereditary. Other things that can cause it include:
injury or infection
nutritional or hormonal imbalances
chemotherapy or exposure to toxic substances
autoimmune diseases such as Lyme disease, lupus, and rheumatoid arthritis (RA)
systemic diseases like diabetes, kidney disorders, and certain cancers
vascular disorders
tumors
Approximately 30 percent of neuropathy cases are due to diabetes, according to the Cleveland Clinic. Between 30 and 40 percent of the remaining cases are idiopathic.

Who is at risk for neuropathy?
The National Institute of Neurological Disorders and Stroke estimates that approximately 20 million Americans have peripheral neuropathy. Anyone can develop neuropathy, but risk increases with age.

How is neuropathy diagnosed?
There is no one definitive test for neuropathy. Testing begins with a physical examination and a complete medical history. Tell your doctor about any symptoms you’re experiencing. Be sure to let them know about over-the-counter and prescription medications you’re taking. It’s also important to mention if you’ve been exposed to toxins on the job or at home.
Diagnostic testing may include:
blood work
urinalysis
nerve conduction studies (NCS)
electromyography (EMG)
skin, nerve, and muscle biopsies
Imaging tests may include a CT scan, X-rays, or magnetic resonance imaging (MRI).

How is neuropathy treated?
Peripheral neuropathy can cause permanent damage to nerves if untreated. Treatment will target the cause if it can be determined.
Treatment of idiopathic neuropathy revolves around symptom management. Options include over-the-counter and prescription medications, physical therapy, and occupational therapy.
Mobility aids can help you move around safely if you’re having trouble with balance or walking. These may include special shoes, braces, and canes.
Lifestyle choices can help to improve day-to-day functioning. It’s important to maintain a healthy weight through a balanced diet rich in vitamins and nutrients. It’s also important to get plenty of rest and exercise to tone and strengthen your muscles. Quitting smoking and keeping alcohol consumption to a minimum is healthy and may also help with your neuropathy.
Living with a chronic illness can lead to anxiety and stress. It can be helpful to talk with someone who lives with the same condition. Your doctor can refer you to a local neuropathy support group for additional support.

What is the long-term outlook for neuropathy?
The general prognosis for idiopathic neuropathy is good, even if your symptoms are permanent. There are many effective treatments available for keeping your symptoms in check and helping you lead a comfortable, happy life. Working with your doctor to treat any underlying condition you may have, along with your symptoms, is the ticket to your best outcome in the short and long term.

Article Provided By: Healthline
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Neuopathy Flares

What Makes Neuropathy Flare up? Here Are 4 Common Causes and The Top 3 Solutions
Last Updated on April 16, 2019

Neuropathy can make life far more difficult than it has to be. Of course, there will always be some struggle when it comes managing the pain and the uncomfortable feelings that come with the condition.

For the most part, treatment is straightforward: manage the symptoms that are able to be managed and find ways to cope with the ones that aren’t.
Sadly, there are times when neuropathy can flare up, making management significantly more troublesome.
Being able to understand why neuropathy is flaring up is one of the first steps to preparing, coping, and managing with the condition.
Sometimes, they are even caused by things that are relatively easy to change and fix, meaning that there are some ways that a person can make it easier to deal with neuropathy.
What Causes Neuropathy To Get Worse?
Because neuropathy is a disease that focuses on the nerves of the body, nearly anything can make it flare up. Flare ups are generally classified as an intensifying of the chronic pain that a person is used to, although it often goes back down to its typical level given time.
As neuropathy is a disease concerned with the nerves, anything that affects the nerves can cause a flare up. This can range from the food that a person eats in a day, to the temperature outside, to the way that person lives his or her life. There are many things that can cause a flare up but many of these things are somewhat preventable.
The things that a person physically cannot change, such as the temperature outside, are things that the person can remedy in other ways. This means that once a person knows what common triggers are, it will be easier to avoid them in the future, leading to an easier and more comfortable life.

The Wrong Foods
The food that a person intakes plays a significant role in neuropathy symptoms. As many people have come to learn, the kinds of foods that can affect it are generally grains, sugars, gluten, and fat. In particular, refined grains have a high glycemic content in them.
This will greatly affect a person’s blood sugar. Diabetic neuropathy is one of the most common forms of neuropathy, meaning that it is crucial that a person keeps his or her blood sugar at an appropriate level whether or not he or she is diabetic.
If a person eats a lot of refined grains, it is best to replace them with whole grains to prevent this issue with blood sugar.

Likewise, sugar directly correlates to a person’s blood sugar levels. Added sugars are even worse as they are only there for flavor and nothing more.
Especially if a person is diabetic, it is best to avoid foods with added sugar. Too much sugar can cause a flare up as it will cause the blood sugar to fluctuate.
This is one of the most common triggers, especially in people who have diabetic neuropathy. Nutritional deficiencies caused by relying too much on the flavor that added sugars provide can not only worsen neuropathy but they can also cause symptoms in someone who does not have it.
If a person has a gluten allergy, it is common sense that he or she stays away from food with gluten. Managing neuropathy symptoms is all the more reason to stay away from gluten. If a person’s body cannot process gluten, then it can severely worsen the symptoms of neuropathy, causing a flare up. This means that these people should search for gluten-free products to avoid these symptoms.
Lastly, saturated fats can cause inflammation, which is definitely a trigger for a neuropathy flare up. If a person does not already have type 2 diabetes, too much saturated fat can put this person on the road to developing diabetes.
To prevent this, the best thing that a person can do is find foods that don’t have a lot of saturated fats in them. Ultimately, the best thing that a person can do to alter any food-related triggers for neuropathy is to avoid sugars, refined grains, gluten, and saturated fat. This will take care of some of the triggers for flare ups.
Poor Physical Health
Since neuropathy is focused on the nerves in the body, the physical health of a person’s body will of course play a big role in how often neuropathy flare ups happen. Some major triggers for a flare up could be smoking, injuries, and illnesses. For instance, it is a well-known fact that smoking is very bad for the human body.

Smoking is one of the many triggers, because smoking constricts the blood vessels in the body, which constricts the blood that goes to the extremities.
This can quickly and easily worsen the symptoms of neuropathy, ultimately resulting in a flare up that nobody wants to deal with.
In addition to this, it should be relatively obvious that injuries to the body can cause a flare up as they can open many nerve endings to more pain that a person typically experiences.
On the chance that a person’s extremities have become so numb that the person is not aware of an injury, it is imperative that this person regularly checks to ensure that there are no injuries on the feet or hands. An injury can put a lot of physical stress on the body, which can lead to a neuropathic nightmare.
As the health of a person’s body plays a large role in whether or not the person is nearing a flare up, another thing that is important to pay attention to is health. Being sick puts quite a bit of stress on the body and thus the nerves. The stress on the nerves can translate into a neuropathic flare up, which can only make dealing with the sickness even worse.
In some cases, underlying issues can even be the cause of the neuropathy in the first place. If a person has any reason to suspect being sick, it would be a good idea to visit the doctor. Besides visiting the doctor, a person should take the appropriate measures to stay as healthy as possible both physically and mentally, to avoid worsening conditions.
Poor Mental and Emotional Health
Just as physical stress plays an enormous role in whether or not a person’s body is at risk for a flare up, mental stress and temperature also play a role. Emotional stress, while people might not think about it much, can be extremely hard on the nerves. This can make emotional stress a trigger for a neuropathic flare up.

One of the ways that a person could alleviate and remove this trigger is to make sure that there isn’t really anything stressful going on.
If there is something stressful, measures should be taken to remove that stressor, whether that means taking care of a particular task or ignoring some people for a period of time.

The temperature of a room or location also plays into the idea of triggers both emotional and physical.
After all, temperature is signaled to the brain through the nerves. Depending on the type of neuropathy a person has, temperature can quickly become a trigger for a flare up.
Typically, cooler temperatures are better, although the change should be gradual so as not to jolt the nerves too much. Cooler temperatures are best as they cause a slower heart rate and slow blood flow a little bit, slightly numbing any pain that a person might be feeling.

Contradicting Medications

Anything that is ingested into the body is going to affect the health of nerves and this especially goes for medication.
Medication can bring about worse side effects that can trigger a neuropathic flare up that nobody wants to deal with.
This can be difficult to deal with as finding the medication that is causing the flare up can be tough. Sometimes, that medication is something that a person needs.
When this happens, it might be worth talking to a doctor about alternatives to reduce the chances that a person’s own medication is causing symptoms to get worse.
How Can They Be Prevented?
Out of the many things that cause flare ups, there are several that can easily be changed. With time, diet and nutrition can change to a more suitable situation for a person’s needs. Stress will come and go with time and managing that stress will be important in regulating flare ups.
Know Your Triggers
Making sure that a person knows what his or her triggers are is essential in preventing flare ups from happening. This means that one of the best things a person can do is keep track of what came before a flare up so that he or she can get a good idea of what triggers neuropathic flare ups. Once the person understands what causes the flare ups, the hard work is halfway done.
Optimize Your Lifestyle
All that needs to be done now is changes in lifestyle to create a life where a person doesn’t have to worry nearly as much about triggering a neuropathic flare up. By having a journal that logs what triggers are and what can be done to avoid them, a person can begin taking the steps needed to live a life without neuropathic flare ups.
Take Supplements
Nutritional supplementation is a safe, low cost way to provide your nerves with the right herbs, vitamins, and nutrition they need for proper functioning. Many people are deficient in key vitamins like thiamine and methyl b12 due to lower nutrient density in today’s foods. People can either take multiple nerve health supplements individually or use a pre-formulated solution like Nerve Renew, which consists of proven ingredients in the optimal dosages according to clinical studies.

Article Provided By: Nerve Pain Guide

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Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy-Induced Peripheral Neuropathy
Timothy J Brown, MD; Ramy Sedhom, MD; Arjun Gupta, MD
Article Information
JAMA Oncol. 2019;5(5):750. doi:10.1001/jamaoncol.2018.6771

Peripheral neuropathy refers to symptoms arising from damage to peripheral nerves. These nerves carry sensation, control movements of the arms and legs, and control the bladder and bowel. Chemotherapy and other drugs used to treat cancer can cause peripheral neuropathy. This is termed chemotherapy-induced peripheral neuropathy (or CIPN).

What Increases the Risk of Developing CIPN?
Certain chemotherapy drugs are more likely to cause neuropathy. These include: platinum drugs, such as oxaliplatin; taxanes, such as docetaxel; vinca alkaloids, such as vincristine; and myeloma treatments, such as bortezomib.
Other chemotherapy drugs can also cause neuropathy. The risk of developing CIPN is higher with higher doses, multiple courses, and combination chemotherapy. Patients are more likely to develop CIPN if they are older or have diabetes, vitamin deficiencies, or preexisting peripheral neuropathy.
How Can I Reduce My Risk of Developing CIPN?
No medication or supplement has been shown to definitively prevent CIPN. Regular exercise, reducing alcohol use, and treating preexisting medical conditions (vitamin B12 deficiency) may reduce the risk of CIPN.
What Are the Symptoms and Complications of CIPN?
Depending on the nerves affected, symptoms include:

Tingling (“pins and needles”)
Pain, which may be severe and constant, may come and go, or may feel like burning
Decreased sensation (“legs feel like jelly”)
Increased sensitivity to touch, temperature, pressure, pain
Muscle weakness

Symptoms can appear hours to days after chemotherapy and may reduce in intensity with time. Commonly, symptoms occur weeks to months after chemotherapy. They can get worse with additional cycles of chemotherapy.
What Should I Do If I Develop Symptoms?
You should notify your care team. Symptoms are likely to worsen if not addressed. Your oncologist can diagnose CIPN based on symptoms and by examining you. Specialized testing is rarely needed.
I Have CIPN—What Now?
One should avoid injury by paying attention to home safety, such as by using handrails on stairs to prevent falls and potholders in the kitchen to avoid burns. Your oncologist may choose to discontinue or reduce the dose of a chemotherapy drug. Your oncologist may recommend over-the-counter pain medications, lidocaine patches, menthol creams, or a medication called duloxetine. Physical therapy, occupational therapy, and rehabilitation may be helpful to regain function. Studies are researching how novel therapies (biofeedback or scrambler therapy) can help. Improvements in function may be gradual. In some cases, nerve damage may be permanent.

Article Provided By: JAMA

 

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Scrambler Therapy for Treating Neuropathic Pain

Scrambler Therapy for Treating Neuropathic Pain
December 9, 2016
by Dr. Thomas Smith and Dr. Charles Loprinzi

What is neuropathic pain, from the non-expert oncologist’s point of view?
The way we think of it, pain is about the most protective instinct and impulse known to humans! If you touch a hot plate, you retract your hand even before you actually feel the pain. Then, the pain comes – very localized – such that you can plunge the hand into cold water. After that, usually the pain goes away and you can then blame your son-in-law for leaving the hot plate on. But sometimes, the pain signal gets stuck in the “on” position, even though your hand has healed. There has been some damage to the nerve endings, and they are continuing to send the “pain” impulse when it is not doing you any good. The pain pathways in the spinal cord and the brain actually get bigger and more active; neurologists call this “wind-up.”
Pain has come to the attention of most oncologists because we CAUSE it with chemotherapy agents; we call it chemotherapy induced peripheral neuropathy (CIPN).
For the unfortunate 40-70% of chemo patients who get CIPN, it can range from being a nuisance to being life-destroying. Our patients describe constant burning or pins-and-needles pain, with numbness and tingling. It starts in the longest nerves that go to the hands and feet first, then progresses upstream. For many people it is just an inconvenience, and goes away in between chemo cycles and abates after treatment. But for others it persists, for years.
Preventing or treating CIPN has been frustrating. We both were part of the American Society of Clinical Oncology panel that made national clinical practice guidelines for CIPN. There are no drugs proven to prevent it, and alpha-lipoic acid, Vitamin A, natural products, L-carnitine – things that help in other neuropathies – were no better than placebo. Only one drug is proven to help, duloxetine (Cymbalta), with a reduction in pain of about 1 point on a 10 point scale.
Of course, there are other neuropathic pains that oncologists know all too well. The pain from a pinched nerve leaving a collapsed or damaged vertebra, shooting down the leg. The pain after shingles, “post-herpetic neuropathy” that can last for years. The pain after chest surgery, or mastectomy, or radiation.

What is Scrambler Therapy, and How Does it Work?
Scrambler Therapy (marketed as Calmare™ therapy in the United States) is a new type of pain relief that uses a rapidly changing electrical impulse to send a “non-pain” signal along the same pain fibers that are sending the “pain” stimulus. We got interested in Scrambler Therapy because we thought it MIGHT help CIPN patients, and Scrambler Therapy appeared to be non-toxic. It had been cleared for safety by the FDA in 2009.
We were skeptical, but we did a trial of Scrambler Therapy. We treated 16 patients with refractory CIPN (present for at least 6 months, and refractory to medications); the group had a 60% reduction in their CIPN pain – in 10 days of treatment. Of the 16 patients we treated, essentially all reported some benefit, including 4 whose pain resolved to “0.” Function improved in most patients including less interference with walking and sleeping, for at least 3 months.
The setup is simple as shown in Figure 1 (Tom Smith’s legs). EKG electrodes are used to transmit the electrical impulses from a colored electrode to a black one, back and forth. The treatment is given for 30-45 minutes for up to 10 days in a row (excluding weekends). Our patients report a feeling like being bitten by electrical ants, or bee-stings. If the treatment is working, the sensation will change to a “hum” in the nerve and go to the ends of the nerve. We have to start above the painful area – remember, we are trying to replace the pain with a “non-pain” stimulus, and sometimes can work progressively down the legs and arms as pain relief occurs. A typical setup to treat “stocking and glove neuropathy”
Colleagues at Mayo Clinic were skeptical and repeated the study in a larger group of people with CIPN. Pachman, Loprinzi and colleagues at Mayo reported about a 50% reduction in pain, numbness and tingling lasting at least 3 months. Of note, there appeared to be a learning curve, with the later patients getting better and longer lasting pain relief.
We will be the first to note that Scrambler Therapy lacks the “Good Housekeeping Seal of Approval” of cancer treatments – the well-designed, large, high statistical power, randomized controlled trial. We are both doing randomized trials, comparing Scrambler Therapy to “sham” (electrodes in the wrong place” and to TENS (trans-cutaneous electrical stimulation).
That said, we are interested in treatments that might work and don’t cause side effects. A recent review of at least 20 scientific reports noted no harm in any trial, with most reporting a substantial relief of pain. The two randomized trials comparing “sham” to real Scrambler Therapy showed a 50% reduction in low back pain, and a 91% reduction in pain from failed back syndrome, post herpetic neuropathy, and spinal cord stenosis. In all the trials, pain relief – if it happened – was obvious in the first 3 days, continued to get better, and usually lasted several months. There are additional reports of Scrambler Therapy having success in cancer somatic pain including bone and visceral metastases, complex regional pain syndrome, pediatric cancer chest wall pain, and others (see list below). The US Military has 17 Scrambler Therapy machines for treating both wounded warriors and civilians.
Some types of pain for which Scrambler Therapy has been used
Pancreas and abdominal cancer pain
Chemotherapy induced peripheral neuropathy
Non cancer pain such as neuropathic back pain
Post-herpetic pain (shingles pain)
Bone metastases
Spinal cord stenosis
“Failed back syndrome” – after surgery, the back hurts worse
Complex regional pain syndrome
Post-mastectomy pain

Is Scrambler Therapy Related to Anything Similar?
Scrambler Therapy looks superficially likes TENS therapy. TENS applies similar electrodes on the skin and passes a pulse of electrical current between them. TENS is a completely different type of on-off current, and, classically, the effect wears off as soon as the electrodes are removed. When Scrambler Therapy works, it seems to reset or reboot the system for an extended period of time.
Spinal cord stimulation appears to have a same effect on pain that Scrambler Therapy appears to have. However, it involves putting electrodes on the spinal cord, and implantation of a pulse generator, similar to a pacemaker. It is also expensive – typically near $100,000 for a trial, then surgery and the equipment. It can last for years.

Is Scrambler Therapy Covered by Insurance?
Quick answer, no, not very well yet. They are waiting for more traditional evidence (unlike the U S Military!) Some places are doing it for free on the clinical trials listed on clinicaltrials.gov. There is a list of certified centers on the Calmare website. An increasing number of insurers are paying for Scrambler if the person and their doctor appeals with lots of evidence from the trials above.
The machines themselves are expensive ($105,000 was the last quote we got) but can be used for a new person each hour, and last for years. The electrodes cost $4-15 dollars per person for a course of treatment. A person with training can do the treatment supervised by a physician with knowledge of the nervous system.

What research needs to be done before Scrambler Therapy is proven effective, and reimbursed if it is?
We have been using Scrambler Therapy routinely at our centers, and believe there is benefit to some patients. At the same time, we are humbled by the many therapies that have shown promise in phase II trials only to be no better than placebo or sham in Phase III trials. We need bigger randomized trials, sponsored by the NIH or someone who is not trying to sell the machines.

Dr. Thomas Smith is the Director of Palliative Medicine, Harry J. Duffey Family Professor of Palliative Medicine, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Dr. Charles Loprinzi is Regis Professor of Breast Cancer Research, Mayo Clinic

Article Provided By: foundationforpn

 

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Femoral Neuropathy

Femoral Neuropathy

What is femoral neuropathy?

Femoral neuropathy, or femoral nerve dysfunction, occurs when you can’t move or feel part of your leg because of damaged nerves, specifically the femoral nerve. This can result from an injury, prolonged pressure on the nerve, or damage from disease. In most cases, this condition will go away without treatment. However, medications and physical therapy may be necessary if symptoms don’t improve.

What causes femoral neuropathy?

The femoral nerve is one of the largest nerves in your leg. It’s located near the groin and controls the muscles that help straighten your leg and move your hips. It also provides feeling in the lower part of your leg and the front of your thigh. Because of where it’s located, damage to the femoral nerve is uncommon relative to neuropathies caused by damage to other nerves. When the femoral nerve is damaged, it affects your ability to walk and may cause problems with sensation in your leg and foot. View the femoral nerve on this BodyMap of the femur.

Damage to the femoral nerve can be the result of:

  • a direct injury
  • a tumor or other growth blocking or trapping part of your nerve
  • prolonged pressure on the nerve, such as from prolonged immobilization
  • a pelvic fracture
  • radiation to the pelvis
  • hemorrhage or bleeding into the space behind the abdomen, which is called the retroperitoneal space
  • a catheter placed into the femoral artery, which is necessary for certain surgical procedures

Diabetes may cause femoral neuropathy. Diabetes can cause widespread nerve damage due to fluctuations in blood sugar and blood pressure. Nerve damage that affects your legs, feet, toes, hands, and arms is known as peripheral neuropathy. There is currently some debate about whether femoral neuropathy is truly a peripheral neuropathy or a form of diabetic amyotrophy.

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), diabetes is the most common reason for peripheral neuropathy in people who’ve had diabetes for at least 25 years.

Signs of femoral neuropathy

This nerve condition can lead to difficulties moving around. Your leg or knee might feel weak, and you may be unable to put pressure on the affected leg.

You might also feel unusual sensations in your legs. They include:

  • numbness in any part of the leg (typically the front and inside of the thigh, but potentially all the way down to the feet)
  • tingling in any part of the leg
  • dull aching pain in the genital region
  • lower extremity muscle weakness
  • difficulty extending the knee due to quadriceps weakness
  • feeling like your leg or knee is going to give out (buckle) on you
How serious is it?

Prolonged pressure placed on the femoral nerve can prevent blood from flowing in the affected area. The decreased blood flow can result in tissue damage.

If your nerve damage is the result of an injury, it may be possible that your femoral vein or artery is also damaged. This could cause dangerous internal bleeding. The femoral artery is a very large artery that lies close to the femoral nerve. Trauma often damages both at the same time. Injury to the artery or bleeding from the artery can cause compression on the nerve.

Additionally, the femoral nerve provides sensation to a major portion of the leg. This loss of sensation can lead to injuries. Having weak leg muscles can make you more prone to falling. Falls are of particular concern in older adults because they can cause hip fractures, which are very serious injuries.

 

Diagnosing femoral neuropathy

Initial tests

To diagnose femoral neuropathy and its cause, your doctor will perform a comprehensive physical exam and ask questions about recent injuries or surgeries, as well as questions about your medical history.

To look for weakness, they will test specific muscles that receive sensation from the femoral nerve. Your doctor will probably check your knee reflexes and ask about changes in feeling in the front part of the thigh and the middle part of the leg. The goal of the evaluation is to determine whether the weakness involves only the femoral nerve or if other nerves also contribute.

Additional testing might include:

Nerve conduction

Nerve conduction checks the speed of electrical impulses in your nerves. An abnormal response, such as a slow time for electrical signals to travel through your nerves, usually indicates damage to the nerve in question.

Electromyography (EMG)

Electromyography (EMG) should be performed after the nerve conduction test to see how well your muscles and nerves are working. This test records the electrical activity present in your muscles when the nerves that lead to them are active. The EMG will determine whether the muscle responds appropriately to stimulation. Certain medical conditions cause muscles to fire on their own, which is an abnormality that an EMG can reveal. Because nerves stimulate and control your muscles, the test can identify problems with both muscles and nerves.

MRI and CT scans

An MRI scan can look for tumors, growths, or any other masses in the area of the femoral nerve that could cause compression on the nerve. MRI scans use radio waves and magnets to produce a detailed image of the part of your body that is being scanned.

A CT scan can also look for vascular or bone growths.

Treatment options

The first step in treating femoral neuropathy is dealing with the underlying condition or cause. If compression on the nerve is the cause, the goal will be to relieve the compression. Occasionally in mild injuries, such as mild compression or a stretch injury, the problem may resolve spontaneously. For people with diabetes, bringing blood sugar levels back to normal may alleviate nerve dysfunction. If your nerve doesn’t improve on its own, you’ll need treatment. This usually involves medications and physical therapy.

Medications

You might have corticosteroid injections in your leg to reduce inflammation and get rid of any swelling that occurs. Pain medications can help relieve any pain and discomfort. For neuropathic pain, your doctor may prescribe medications, such as gabapentin, pregabalin, or amitriptyline.

Therapy

Physical therapy can help build up the strength in your leg muscles again. A physical therapist will teach you exercises to strengthen and stretch your muscles. Undergoing physical therapy helps to reduce pain and promote mobility.

You might need to use an orthopedic device, such as a brace, to assist you with walking. Usually, a knee brace is helpful in preventing knee buckling.

Depending on how severe the nerve damage is and how much trouble you’re having moving around, you might also need occupational therapy. This type of therapy helps you learn to do regular tasks like bathing and other self-care activities. These are called “activities of daily living.” Your doctor might also recommend vocational counseling if your condition forces you to find another line of work.

Surgery

Your doctor might recommend surgery if you have a growth blocking your femoral nerve. Removing the growth will relieve the pressure on your nerve.

Long-term outlook after treatment

You might be able to heal fully after you treat the underlying condition. If the treatment isn’t successful or if the femoral nerve damage is severe, you might permanently lose feeling in that part of your leg or the ability to move it.

Tips to prevent nerve damage

You can lower your risk of femoral neuropathy caused by diabetes by keeping your blood sugar levels under control. This helps protect your nerves from damage caused by this disease. Preventive measures would be directed at each cause. Talk to your doctor for advice about what preventive measures would be the best for you.

Maintaining an active lifestyle helps to keep your leg muscles strong and improve stability.

Last medically reviewed on September 13, 2017

 

Article Provided ByHealthline

 

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Nerve Pain Therapy, Pain Therapy, Chronic Pain, Calmare Scrambler, Chronic Pain Therapy, Neuropathic Pain Therapy, Greenville SC

Sacroiliac Joint Dysfunction

Sacroiliac Joint Dysfunction

Dysfunction in the sacroiliac joint is thought to cause low back pain and/or leg pain. The leg pain can be particularly difficult and may feel similar to sciatica or pain caused by a lumbar disc herniation. The sacroiliac joint lies next to the bottom of the spine, below the lumbar spine and above the tailbone (coccyx). It connects the sacrum (the triangular bone at the bottom of the spine) with the pelvis (iliac crest).

The joint typically has the following characteristics:

  • Small and very strong, reinforced by strong ligaments that surround it
  • Does not have much motion
  • Transmits all the forces of the upper body to the pelvis (hips) and legs
  • Acts as a shock-absorbing structure

Symptoms

The most common symptoms for patients are lower back pain and the following sensations in the lower extremity: pain, numbness, tingling, weakness, pelvis/buttock pain, hip/groin pain, feeling of leg instability (buckling, giving way), disturbed sleep patterns, disturbed sitting patterns (unable to sit for long periods, sitting on one side), pain going from sitting to standing.


Causes and Risk Factors

While it is not clear how the pain is caused, it is thought that an alteration in the normal joint motion may be the culprit that causes sacroiliac pain. This source of pain can be caused by either:

Too much movement (hypermobility or instability): The pain is typically felt in the lower back and/or hip and may radiate into the groin area.

Too little movement (hypomobility or fixation): The pain is typically felt on one side of the lower back or buttocks and can radiate down the leg. The pain usually remains above the knee, but at times pain can extend to the ankle or foot. The pain is similar to sciatica — or pain that radiates down the sciatic nerve — and is caused by a radiculopathy.

Diagnosis

Accurately diagnosing sacroiliac joint dysfunction can be difficult because the symptoms mimic other common conditions, including other mechanical back pain conditions like facet syndrome and lumbar spine conditions including disc herniation and radiculopathy (pain along the sciatic nerve that radiates down the leg). A diagnosis is usually arrived at through physical examination (eliminating other causes) and/or an injection (utilized to block the pain).

Treatments

Treatments for sacroiliac joint dysfunction are usually conservative (meaning nonsurgical) and focus on trying to restore normal motion in the joint:

  • Ice, heat and rest.
  • Medications: acetaminophen, as well as anti-inflammatory medications (such as ibuprofen or naproxen) to reduce the swelling that is usually contributing to the patient’s pain.
  • Manual manipulation provided by a chiropractor, osteopathic doctor or other qualified health practitioner may help. This can be highly effective when the sacroiliac joint is fixated or “stuck.” It may be irritating if the sacroiliac joint is hypermobile. The manipulation is accomplished through a number of methods, including (but not limited to): side-posture manipulation, drop technique, blocking techniques and instrument-guided methods.
  • Supports or braces for when the sacroiliac joint is “hypermobile,” or too loose.
  • Controlled, gradual physical therapy may be helpful to strengthen the muscles around the sacroiliac joint and appropriately increase range of motion. In addition, any type of gentle, low-impact aerobic exercise will help increase the flow of blood to the area, which in turn stimulates a healing response. For severe pain, water therapy may be an option, as the water provides buoyancy for the body and reduces stress on the painful joint.
  • Sacroiliac joint injections.

When these treatments fail, surgery may be offered. In surgery, one or both of the sacroiliac joints may be fused with the goal of eliminating any abnormal motion.

Article Provided By: Cedars-Sinai

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Sciatica

Six sciatica stretches for pain relief

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Sciatica itself is not a condition, but a very uncomfortable symptom of many potential problems in the back, pelvis, and hip.

People with sciatica often experience pain running through the buttocks and down the back of the leg. However, it does not have to originate in the back; it can be caused by an injury to the pelvis or hip, or from direct pressure to the sciatic nerve.

The pain can be mild or so severe that a person with sciatica may have trouble standing, sitting, or even sleeping. There is a range of treatments for sciatica, including many stretches that may help to ease the pain.

Overview
People with sciatica can experience pain that makes it difficult for them to sit or stand.

The sciatic nerve is a nerve that originates in the lower back on either side of the spine. It runs through the buttocks and into the hips before branching down each leg.

This nerve is the longest nerve in the body and provides sensation to the outer leg and foot.

Sciatica itself is not an injury or disease. Instead, sciatica refers to a symptom of any number of problems.

Sciatica is nerve pain that runs through the buttocks, down the back of the leg and into the ankle or foot.

Some people that have sciatica describe the pain as shooting, sharp, or burning. They may experience weakness in the affected leg. The pain may worsen with sudden movements, such as coughing.

Stretches for pain relief

Certain stretches may provide some relief for people experiencing sciatica-related pain.

Anecdotally, most people with sciatica do find stretching helps relieve pain. However, people with sciatica should speak to a doctor before doing any sciatica stretches to avoid further injury.

A doctor or physical therapist may recommend that people perform several of these stretches each day:

  • knees to chest
  • cobra or modified cobra
  • seated hip stretch
  • standing hamstring stretch
  • seated spinal twist
  • knee to shoulder

Follow these simple instructions to perform these stretches for sciatica pain relief:

If any of these exercises make the sciatica worse, stop immediately. It is normal to feel stretching during these movements, however it is not normal for the sciatic pain to increase.

Treatment

As well as stretching, some people who experience sciatica symptoms also try other home remedies to ease their pain and discomfort.

Other home remedies include the following:

  • Ice: Icing the area for 20 minutes several times a day for the first two to three days after the pain begins.
  • Heat: Using heat on the area after the first few days.
  • Anti-inflammatories: Taking anti-inflammatory medications to ease the pain. Ibuprofen is available for purchase over-the-counter or online.

Anyone that experiences sciatica for longer than a month should seek medical attention. Additionally, any person that has severe sciatica should seek medical care as soon as possible.

Treatment for an individual’s sciatica largely depends on what is causing the pain.

Some common causes of sciatica include the following:

  • herniated disc or one of the rubbery cushions between the spinal bones slipping out of place
  • a narrowing of the spinal cord that puts pressure on the lumbar spine known as lumbar spinal stenosis
  • a progressive disease that wears away the cushions in the spinal column known as degenerative disk disease
  • pregnancy
  • other injuries to the back that put excess pressure on the sciatic nerve
Prevention

It is not always possible to prevent sciatica. However, some lifestyle modifications can significantly help reduce a person’s risk of experiencing sciatica again.

In general, regular exercise and building a strong core may help prevent sciatica. Additionally maintaining a good posture while sitting and standing is important, and may make people less likely to develop sciatica than people with poor posture.

Article Provided By: medicalnewstoday

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Why You Need Hope

Why You Need Hope

“Is there hope?” is a question I hear often. One of my patients struggling with a low back injury recently mentioned that doctors keep telling her that there is no hope. The look on her face told me how upsetting this was for her, and she asked me, “What do you think?”

Before I tell you my answer, I first want to be clear about why both the question and the answer matter.

Broadly defined, hope is a feeling or expectation for a desired outcome. Using standardized tests like the Hope Scale, a number of different studies looking at the impact of hope on chronic disease suggests that it is associated with improved outcomes. Higher levels of hope often correlate with increased life satisfaction scores, better lifestyle habits, and lower levels of depression and anxiety. Cardiovascular problems seem to recover more favorably in patients that are more hopeful.

When it comes to chronic pain conditions, whether it be back pain, fibromyalgia, or migraines, experiencing constant pain can easily squeeze hope out. You want to stay optimistic and have a positive outlook, but the more you hurt, the more you start to question whether or not good times can lie ahead. Behavioral health researchers sometimes refer to this as emotional conflict, meaning all of this worrying about your future starts to take a toll.

Interestingly, a certain part of the brain, known as the rostral anterior cingulate cortex, seems to play an important role in boosting hope. In theory, the right thoughts or mindset generated from there help trigger a surge in more positive feelings or emotions in the brain’s emotional processing center called the amygdala, and this, in turn, activates behavior changes that eventually lead to accomplishing desired goals. The key step is mustering the right outlook to set this reaction in motion, and this is where folks can get stuck. If you start off with the notion that “This condition is chronic and won’t go away, and therefore, there is no hope,” then this plane will never get off the ground.

When doctors told my patient that there was no hope because she had a chronic condition, they zapped the air out of her sails, because they forced her to adopt the wrong mindset. Deep inside each of us is a human spirit with a core mission and a set of beliefs and values that spin off their own set of goals. Her outlook dramatically improved once I reminded her of all that she had accomplished since I had known her and how she was actually on the right path toward reaching her goals. We started to talk about how she was doing all of the right things, and if she stuck with the process, then her quality of life had a great chance of continuing to improve. Heck ya, there was hope!

Having a rosy outlook when things are going well is one thing, but seeing a glimmer of light when things seem to be at their darkest can pose a bigger challenge. The first step is finding that all-important spark that can rekindle hope, and then you can build your path forward based on the hope, not the pain.

 

Why You Need Hope  BY PETER ABACI, MD

 

 

 

Carolina Pain Scrambler Logo, Chronic Pain, Greenville, SC

 

If you would like to discuss what Carolina Pain Scrambler do to help relieve your chronic pain symptoms or receive more information on our treatment process, please do not hesitate to call us at 864-520-5011 or you can email us at info@carolinapainscrambler.com

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